工作經(jīng)歷
2012.7- 中國科學(xué)院國家數學(xué)與交叉科學(xué)中心生物醫學(xué)部 助理研究員 2012.7- 中國科學(xué)院數學(xué)與系統科學(xué)研究院 助理研究員
主要成就
在Nature子刊、Nucleic Acids Research、Bioinformatics、Briefings in Bioinformatics等國際權威期刊以第一作者和通訊作者身份發(fā)表生物信息學(xué)相關(guān)領(lǐng)域論文18篇，第一作者14篇, 通訊作者10篇，發(fā)表論文目前共被引用302次，參編專(zhuān)著(zhù)4部，獲得授權專(zhuān)利1項，曾獲國際網(wǎng)絡(luò )博弈論大會(huì )最佳論文獎、中科院數學(xué)院院長(cháng)獎學(xué)金、博時(shí)獎學(xué)金、永安期貨獎學(xué)金、英達獎學(xué)金、第四屆世界華人數學(xué)家大會(huì )新世界數學(xué)獎、美國數學(xué)建模競賽國際一等獎等榮譽(yù)，主持或以骨干身份參與 國家自然科學(xué)基金重大研究計劃、國家自然科學(xué)基金青年基金等11項重要項目.
著(zhù)作成果
Predicting lncRNA-disease associations and constructing lncRNA functional similarity network based on the information of miRNA Scientific Reports:2015,5:13186 (SCI 影響因子5.578, nature旗下,獨立作者) Drug–target interaction prediction: databases, web servers and computational models Briefings in Bioinformatics: 2015 ,In press (SCI 影響因子9.617,第一作者和通訊作者) RBMMMDA: predicting multiple types of disease-microRNA associations Scientific Reports:2015,5: 13877 (SCI 5.578, nature旗下,第一作者和通訊作者) Constructing lncRNA functional similarity network based on lncRNA-disease associations and disease semantic similarity Scientific Reports. 2015 5:11338 (SCI 5.578, nature旗下,第一作者和通訊作者) Distributed Image Understanding with Semantic Dictionary and Semantic Expansion Neurocomputing:2015,In press (SCI 2.083) Semi-supervised learning for potential human microRNA-disease associations inference Scientific Reports. 2014,4:5501 (SCI 5.078, nature旗下,被引用10次,第一作者和通訊作者) 2012－2013運籌學(xué)學(xué)科發(fā)展報告 中國運籌學(xué)會(huì ).中國科學(xué)技術(shù)出版社:,2014 ASDCD: Antifungal Synergistic Drug Combination Database PLOS ONE:2014,9(1): e86499 (SCI 3.73 第一作者). Large Scale Image Understanding with Non-convex Multi-task Learning The 2014 5th International Conference on Game Theory for Networks:2014,Best Paper Award. Novel human lncRNA-disease association inference based on lncRNA expression profiles Bioinformatics:2013,29(20),2617-2624 (SCI 5.323, 2/47 in Mathematical & Computational Biology,被引用12次,第一作者和通訊作者) A computational framework to infer human disease-associated long noncoding RNAs PLOS ONE:2014,9(1): e84408 (SCI 3.73，被引用13次). LncRNADisease: a database for long-non-coding RNA-associated diseases Nucleic Acids Research:2013,41(Database issue),D983--D986 (SCI: 8.026, 26/289 in Biochemistry and Molecular Biology，被引用120次). Drug-Target Interaction Prediction by Random Walk on the Heterogeneous Network Molecular BioSystems:2012,8(7)1970-1978 (SCI 3.825，被引用52次 Top ten most accessed articles),in June 2012;Top 10% of the most highly cited articles published in the latest Impact Factor window (2011-2012), 第一作者). RWRMDA: predicting novel human microRNA-disease associations Molecular BioSystems:2012,8(10),1970-1978 (SCI 3.825, 被引用33次，第一作者). Prediction of disease-related interactions between microRNAs and environmental factors based on a semi-supervised classifier PLoS ONE:2012,7(8),e43425 (SCI 4.092,第一作者,被引用12次，第一作者) A novel candidate disease genes prioritization method based on module partition and rank fusion OMICS: A Journal of Integrative Biology:2010,14 (4),337-356 (SCI 3.17，被引用13次,第一作者和通訊作者). 多階段多目標多部門(mén)應急決策模型 系統工程理論與實(shí)踐:2010,30(11),1977-1985 (EI 0.896，被引用23次,第一作者和通訊作者). NRWRH for drug target prediction The 4th International conference on computational Systems Biology:2010,13,219-226 (ISTP, 第一作者和通訊作者). Modularized random walk with restart for candidate disease genes prioritization Optimization and Systems Biology:2009,11,353-360 (ISTP, 第一作者和通訊作者).